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short-chain fatty acid

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By Targets:	Free Fatty Acid Receptor (3) Apoptosis (1) Biochemical Assay Reagents (2) Endogenous Metabolite (1) Fungal (1) Isotope-Labeled Compounds (3) Potassium Channel (1) TET Protein (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (4) Neurological Disease (1)

15

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Natural
Products

3

Isotope-Labeled Compounds

Targets Recommended: Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH Amino Acid Derivatives Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

L-Arginine butanoate Maximum Cited Publications 8 Publications Verification (S)-(+)-Arginine butanoate	Others	Others
L-Arginine butanoate ((S)-(+)-Arginine butanoate) is a compound consisting of L-Arginine and butanoate. L-Arginine is one of the essential nutrients in the human body and participates in various biochemical processes. Butanoate is a short-chain fatty acid commonly used as a food additive and solvent in pharmaceutical formulations .

AMG7703	Free Fatty Acid Receptor	Metabolic Disease Inflammation/Immunology
AMG7703 is a selective and allosteric agonists of FFA2 (GPR43), the receptor for short-chain fatty acids (SCFAs), acetate, and propionate. AMG7703 can be used to research for in inflammatory and metabolic .

3-(3,4-Dimethoxyphenyl)propanoic acid
3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias .

Tributyrin 1 Publications Verification Glyceryl tributyrate	Apoptosis	Metabolic Disease Cancer
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed proagent of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects .

2-Methylvaleric acid 2-Methylpentanoic acid	Endogenous Metabolite	Metabolic Disease
2-Methylvaleric acid (2-Methylpentanoic acid) is a short-chain fatty acid isolated from Campomanesia adamantium and dairy products. 2-Methylvaleric acid is also found in animal feces. 2-Methylvaleric acid is a flavor compound used for food-flavor ingredient, fragrances .

HY-W015882

4-Methylpentanoic acid

Isocaproic acid
Others Others

4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA) .

3-(3,4-Dimethoxyphenyl)propanoic acid-d10	Isotope-Labeled Compounds	Cardiovascular Disease
3-(3,4-Dimethoxyphenyl)propanoic acid-d₁₀ is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

Isobutyryl coenzyme A lithium Isobutyryl CoA lithium	Biochemical Assay Reagents	Others
Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.

HY-W015882S

4-Methylpentanoic acid-d12 Isocaproic acid-d₁₂	Isotope-Labeled Compounds	Others
4-Methylpentanoic acid-d₁₂ is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA)[1].

2,2-Dibromopropanoic acid	Fungal	Infection
2,2-Dibromopropanoic acid is a dibromo product based on propionic acid. Propionic acid is a short chain fatty acid and acts as chemical intermediate. Propionic acid is also a mold inhibitor and widely used in food preservative .

HY-W015882S1

4-Methylpentanoic acid-d11	Isotope-Labeled Compounds	Others
4-Methylpentanoic acid-d₁₁ is the deuterium labeled 4-Methylpentanoic acid[1]. 4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA)[2].

KOdiA-PC	Biochemical Assay Reagents	Others
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

4-CMTB 2 Publications Verification	Free Fatty Acid Receptor	Others
4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC₅₀=6.38) .

AZ1729	Free Fatty Acid Receptor	Metabolic Disease
AZ1729 is a potent *free fatty* acid 2 receptor (FFA2)** activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in G_i-mediated pathways, but not at those transduced by G_q/G₁₁. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2 .

Succinic acid sodium Wormwood acid sodium	Potassium Channel TET Protein	Neurological Disease
Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten‑eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research .

Cat. No.	Product Name	Category	Target	Chemical Structure

2-Methylvaleric acid 2-Methylpentanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Methylvaleric acid (2-Methylpentanoic acid) is a short-chain fatty acid isolated from Campomanesia adamantium and dairy products. 2-Methylvaleric acid is also found in animal feces. 2-Methylvaleric acid is a flavor compound used for food-flavor ingredient, fragrances .

4-Methylpentanoic acid Isocaproic acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA) .

Cat. No.	Product Name	Chemical Structure

HY-W015882S

4-Methylpentanoic acid-d12

4-Methylpentanoic acid-d₁₂ is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA)[1].

3-(3,4-Dimethoxyphenyl)propanoic acid-d10
3-(3,4-Dimethoxyphenyl)propanoic acid-d₁₀ is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

HY-W015882S1

4-Methylpentanoic acid-d11

4-Methylpentanoic acid-d₁₁ is the deuterium labeled 4-Methylpentanoic acid[1]. 4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA)[2].

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